Differin Gel (0.1% adapalene) is a powerful, dermatologist-developed retinoid for treating mild to moderate acne, available over-the-counter.

It works by unclogging pores, reducing inflammation, and preventing new acne, with visible results often appearing within 2–12 weeks. It is generally applied once daily in a thin layer over the entire face, not just as a spot treatment.

Key Information About Differin Gel
Active Ingredient: Adapalene 0.1%, which is a retinoid that clears acne deep within the pore.
Best Used For: Whiteheads, blackheads, clogged pores, and inflammatory spots.

Application: Apply a pea-sized amount to the entire affected area (not just spots) once daily, preferably at night.
Side Effects: Potential for dryness, irritation, redness, and a burning sensation, especially in the first few weeks.

Precautions: Increases skin sensitivity to sunlight, making SPF 30+ sunscreen mandatory. Do not use if pregnant, planning to become pregnant, or on damaged/sunburned skin.

Results: While it works immediately, it often takes up to 12 weeks for maximum results.
Usage Tips

Cleanse your face and apply a moisturizer before or after the gel to manage dryness.
Consistency is key; skipping days can lead to setbacks.
If irritation occurs, try using it every other day, then gradually increase to once daily.